Opposed to Leganés in the knockout stages of Copa del Rey, FC Barcelona won easily 5-0, thanks in particular to a double from the Argentinian international Messi.
The Frenchman, Griezmann and Lenglet also found the way to the nets, as did the Brazilian Arthur.
Real Madrid had notably crushed Zaragoza Wednesday night at La Romareda (4-0), it is now the turn of FC Barcelona to play its eighth finals in Copa del Rey.
At Camp Nou, the defending Spanish champions received Leganés, another La Liga team, for a place in the next round.
Beaten by Valencia CF this weekend in La Liga (0-2), the Blaugranas (FC Barcelona) had to raise their heads against the Legionarios, who had already spent three laps in this Spanish cup.
After the setback against the club, Quique Setien notably established Lenglet and Vidal. The Frenchman Griezmann was still aligned in front. Opposite, Javier Aguirre opted for a defensive scheme with the former Toulousain at the forefront.